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Can hormonal imbalance contribute to mood disorders?

Yes, hormones are closely tied to brain chemistry and emotional regulation. Imbalances can mimic or worsen anxiety and depression.

Estrogen: Supports serotonin and dopamine. Low estrogen (e.g. in menopause) can trigger irritability, anxiety, or low mood.

Testosterone: Influences motivation, confidence, and resilience. Low levels in men and women can cause apathy, irritability, or mild depression.

Thyroid hormones: Hypothyroidism is linked to depression and brain fog, while hyperthyroidism often causes anxiety and restlessness.

Cortisol: Chronic stress and high cortisol increase sensitivity to stress and can worsen mood swings.

What helps: Addressing hormonal health often improves mood stability. This may involve thyroid optimisation, hormone replacement, or stress management. Psychological support, exercise, and nutrition are also critical.