
Can hormonal imbalance contribute to mood disorders?
Yes, hormones are closely tied to brain chemistry and emotional regulation. Imbalances can mimic or worsen anxiety and depression.
Estrogen: Supports serotonin and dopamine. Low estrogen (e.g. in menopause) can trigger irritability, anxiety, or low mood.
Testosterone: Influences motivation, confidence, and resilience. Low levels in men and women can cause apathy, irritability, or mild depression.
Thyroid hormones: Hypothyroidism is linked to depression and brain fog, while hyperthyroidism often causes anxiety and restlessness.
Cortisol: Chronic stress and high cortisol increase sensitivity to stress and can worsen mood swings.
What helps: Addressing hormonal health often improves mood stability. This may involve thyroid optimisation, hormone replacement, or stress management. Psychological support, exercise, and nutrition are also critical.